Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC IDH889 | 1429179-07-6 | 100.0% | 436.48 | 100 MG
IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). It shows potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM for IDH1R132H, 0.072 μM for IDH1R132C, and 1.38 μM for IDH1wt. IDH889 also demonstrates potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 μM.
- Orally available
- Brain penetrant
- Allosteric and mutant specific IDH1 inhibitor
- Potent selectivity for IDH1 R132* mutations
- Potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production
Medchemexpress LLC Streptomycin | 57-92-1 | 99.9% | 1 G
Streptomycin is an effective antibiotic used in the research of tuberculosis (TB) against M. tuberculosis. It is also a bacteriocidal agent effective against a variety of bacterial infections. It strongly binds to nucleic acids, interfering with and blocking protein synthesis while still allowing RNA and DNA synthesis. Additionally, it functions as a common antibiotic in culture media and blocks stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes.
- Effective antibiotic against M. tuberculosis
- Bacteriocidal agent for research on various bacterial infections
- Interferes with and blocks protein synthesis
- Allows RNA and DNA synthesis to continue
- Common antibiotic in culture media
- Acts as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes
Medchemexpress LLC Streptomycin | 57-92-1 | 99.9% | 500 MG
Streptomycin is an effective antibiotic against M. tuberculosis and is used for the research of tuberculosis (TB). It is also a bacteriocidal agent used for the research of various bacterial infections. Streptomycin binds strongly to nucleic acids, interfering with and blocking protein synthesis while allowing continued RNA and DNA synthesis. Additionally, it functions as a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes, and is a common antibiotic in culture media.
- Effective antibiotic against M. tuberculosis
- Bacteriocidal agent for bacterial infections research
- Interferes with and blocks protein synthesis
- Allows continued RNA and DNA synthesis
- Blocker of stretch-activated and mechanosensitive ion channels
Research Products International Corp Amoxicillin Trihydrate, 25 Grams
Amoxicillin is a broad-spectrum, semi-synthetic penicillin antibiotic that is effective against a wide range of bacteria. The trihydrate form of amoxicillin is a crystalline powder that is often used in laboratory settings.
Amoxicillin inhibits the growth of bacteria by interfering with their cell wall synthesis. It is a versatile antibiotic with low toxicity to mammalian cells, making it a valuable tool in maintaining sterile conditions in cell cultures and studying bacterial physiology.
Researchers use amoxicillin to selectively culture bacteria or to treat bacterial infections in cell cultures.
Medchemexpress LLC HY-12473 5mg Medchemexpress, Vps34-IN-2 CAS:1523404-29-6 Purity:>98%
Medchemexpress, HY-12473 5mg Vps34-IN-2 CAS:1523404-29-6 Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively. Vps34-IN-2 shows antiviral activity against SARS-CoV-2 (IC50 of 3.1 μM), HCoV-229E (IC50 of 0.7 μM) and HCoV-OC43. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Med Vet International Azithromycin Tablets, 250mg, 30ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Azithromycin is an antibiotic used to treat a range of bacterial infections. Azithromycin prevents bacteria from producing the proteins preventing them from multiplying
Medchemexpress LLC L-2-hydroxyglutaric acid | 13095-48-2 | 95.1% | 148.11 | 10 MG
L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. It can inhibit histone demethylases, thereby promoting histone methylation. L-2-Hydroxyglutaric acid also inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki values of 2.52 mM and 11.13 mM, respectively. It is potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs) including the Ten Eleven Translocation (TET) enzymes.
- Epigenetic modifier
- Putative oncometabolite in renal cancer
- Inhibits histone demethylases
- Inhibits mitochondrial creatine kinase (Mi-CK) activity
- Potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs)
- Human endogenous metabolite
Medchemexpress LLC Topilutamide | 260980-89-0 | 99.91% | 403.23 | 100 MG
Topilutamide is a topical nonsteroidal antiandrogen (NSAA) primarily used in prostate cancer research. It is a first-generation nonsteroidal anti-androgen, similar to Flutamide, Nilutamide, and Bicalutamide, and plays a role in treating metastatic prostate cancer.
- Topical nonsteroidal antiandrogen (NSAA)
- Used in prostate cancer research
- First-generation nonsteroidal anti-androgen
Medchemexpress LLC HY-101843 5mg Medchemexpress, ML213 CAS:489402-47-3 Purity:>98%
Medchemexpress, HY-101843 5mg ML213 CAS:489402-47-3 ML213 is a selective activator of Kv7.2 and Kv7.4 channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Medicagenic acid (Castanogenin) | 599-07-5 | MFCD02752364 | 5 MG
Medicagenic acid (Castanogenin) is isolated from the roots of *Herniaria glabra*. It exhibits potent fungistatic effects against several plant pathogens and human dermatophytes. It also shows low enzyme inhibitory activities, targeting enzymes such as xanthine oxidase, collagenase, elastase, tyrosinase, and ChE.
- Isolated from the roots of *Herniaria glabra*.
- Exhibits potent fungistatic effects against several plant pathogens and human dermatophytes.
- Shows low enzyme inhibitory activities.
- Targets enzymes including xanthine oxidase, collagenase, elastase, tyrosinase, and ChE.
Medchemexpress LLC Sacubitrilat | 149709-44-4 | 99.1% | 383.44 | 100 MG
Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor, designed for research use only. It is a single diastereomer that binds to the active site of NEP with high inhibitory potency.
- Active neprilysin (NEP) inhibitor
- Single diastereomer with specific stereocenters
- High inhibitory potency (5 nM)
- For research use only
Apexbio Technology LLC Thioridazine HCl,100mg CAS# 130-61-0
Thioridazine·HCl is a calcium channel protein inhibitor as well as D2DR/D4DR inhibitor. Its administration has been associated with hypotension. It has also been, after chronic treatment, used to test increased sensitivity of dopaminergic agents. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC HY-10013B 2mg Medchemexpress, Taranabant ((1R,2R)stereoisomer) CAS:701977-08-4 Purity:>98%
Medchemexpress, HY-10013B 2mg Taranabant ((1R,2R)stereoisomer) CAS:701977-08-4 Taranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selective cannabinoid 1 ( CB1 ) receptor inverse agonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Lincomycin hydrochloride British Pharmacopoeia (BP) Reference Standard | 859-18-7 | MFCD00083647 |
Lincomycin hydrochloride British Pharmacopoeia (BP) Reference Standard | Mol Wt: 443 | 859-18-7 | MFCD00083647 |
Research Products International Corp Nystatin, 5 Grams
Nystatin is an antifungal polyene antibiotic that is effective against a wide range of fungi, including yeast and molds. It works by binding to the fungal cell membrane, disrupting its integrity and leading to leakage of cellular contents.
Nystatin is particularly useful in preventing and treating fungal contamination in cell cultures, making it a valuable tool in microbiological research. Researchers often use Nystatin to maintain aseptic conditions in cell culture experiments.
It is added to growth media to prevent the overgrowth of fungi that could potentially compromise the integrity of cell lines and experimental results. It is selective for fungi and has minimal toxicity to mammalian cells at effective antifungal concentrations.